Aprepitant

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Inorbvict Healthcare India Pvt Limited

Business Type:Manufacturer

Country/Region:India

Ddu Verified

HOT Rank

6/10

Product Information

  • Pharmacopeia:CP
  • Shelf Life:18 months
  • Storage:Sealed

Description

Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.

Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. It was approved by the FDA in 2003.[1]

Aprepitant may also be useful in the treatment of cyclic vomiting syndrome and late-stage chemotherapy induced vomiting, but there are few studies to date.


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